Necrotizing granuloma

Granuloma

Definition

A granuloma is a clump of cells that forms when the immune system tries to fight off a harmful substance but cannot remove it from the body.

A necrotizing granuloma is an area of inflammation in which tissue has died. Necrotizing means dying or decaying.

Tuberculosis and granulomatosis with polyangiitis are conditions that cause necrotizing granulomas.

References

Jones KD, Urisman A. Histopathologic approach to the surgical lung biopsy in interstitial lung disease. In: Collard HR, Richeldi L, eds. Interstitial Lung Disease. Philadelphia, PA: Elsevier; 2018:chap 12.

Schedule An Appointment

Review Date: 9/9/2023

Reviewed By: Debra G. Wechter, MD, FACS, General Surgery Practice Specializing in Breast Cancer, Virginia Mason Medical Center, Seattle, WA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.


The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. No warranty of any kind, either expressed or implied, is made as to the accuracy, reliability, timeliness, or correctness of any translations made by a third-party service of the information provided herein into any other language. © 1997- A.D.A.M., a business unit of Ebix, Inc. Any duplication or distribution of the information contained herein is strictly prohibited.