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Skin lesion KOH exam

The skin lesion KOH exam is a test to diagnose a .

Your health care provider scrapes the problem area of your skin using a needle or scalpel blade. The scrapings from the skin are placed on a microscope slide. Liquid containing the chemical (KOH) is added. The slide is then examined under the microscope. KOH helps dissolve much of the cellular material. This makes it easier to see if there is any fungus.

There is no special preparation for the test.

You may feel a scratching sensation when the provider scrapes your skin.

This test is done to diagnose a fungal infection of the skin.

No fungus is present.

Fungus is present. The fungus may be related to , , , or another fungal infection.

If the results are uncertain, a may need to be done.

There is a small risk of bleeding or infection from scraping the skin.

Babel DE. Fungal studies (and scabies): collection procedures and tests. In: Fowler GC, ed. Pfenninger and Fowler's Procedures for Primary Care. 4th ed. Philadelphia, PA: Elsevier; 2020:chap 17.

Fitzpatrick JE, High WA, Kyle WL. Diagnostic techniques. In: Fitzpatrick JE, High WA, Kyle WL, eds. Urgent Care Dermatology: Symptom-Based Diagnosis. Philadelphia, PA: Elsevier; 2018:chap 2.

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Contact Atlanta Obsetrics and Gynaecology at The Womens Center Millennium Hospital - 404-ATL-BABY

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Review Date: 6/7/2023

Reviewed By: Elika Hoss, MD, Assistant Professor of Dermatology, Mayo Clinic, Scottsdale, AZ. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.