Treats high blood pressure. This medicine is a combination of an angiotensin receptor blocker (ARB) and a thiazide diuretic (water pill).
Brand Name(s):
There may be other brand names for this medicine.
When This Medicine Should Not Be Used:
This medicine is not right for everyone. Do not use it if you had an allergic reaction to eprosartan, hydrochlorothiazide, or sulfonamide (sulfa) drugs. Do not use this medicine if you are pregnant or not able to urinate.
How to Use This Medicine:
Tablet
Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
Drink plenty of fluids if you exercise, sweat more than usual, or have diarrhea or vomiting.
Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Do not use this medicine together with aliskiren if you have diabetes.
Some medicines can affect how eprosartan/hydrochlorothiazide works. Tell your doctor if you are also using any of the following:
Cholestyramine or colestipol
Insulin or a diabetes medicine that you take by mouth
Lithium
NSAID pain or arthritis medicine (aspirin, celecoxib, diclofenac, ibuprofen, naproxen)
Steroid medicine (such as dexamethasone, hydrocortisone, methylprednisolone, prednisolone, prednisone)
Ask your doctor before you use any medicine, supplement, or salt substitute that contains potassium.
Alcohol, narcotic pain medicine, or sleeping pills may cause you to feel more lightheaded, dizzy, or faint when used with this medicine.
Warnings While Using This Medicine:
It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
Tell your doctor if you are breastfeeding, or if you have kidney problems, liver disease, heart failure, diabetes, glaucoma, gout, lupus, or a history of asthma.
This medicine could lower your blood pressure too much, especially when you first use it or if you are dehydrated. Stand up slowly if you feel lightheaded or dizzy.
This medicine may make you dizzy or drowsy. Do not drive or do anything that could be dangerous until you know how this medicine affects you.
Do not stop using the medicine without asking your doctor, even if you feel well. This medicine will not cure high blood pressure, but it will help keep it in the normal range. You may have to take blood pressure medicine for the rest of your life.
Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Blistering, peeling, red skin rash
Change in how much or how often you urinate
Chest pain, fast or uneven heartbeat
Confusion, trouble breathing, numbness or tingling in your hands, feet, or lips
Dry mouth, increased thirst, muscle cramps, nausea or vomiting
Eye pain, vision changes, seeing halos around lights
Lightheadedness, dizziness, fainting
Unusual tiredness or weakness
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
Last Updated: 6/6/2024
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